SAMHSA Dear Colleague Letter: Updated Guidance On Medication Assisted Treatment/Medication For Opioid Use Disorder

The letter was issued by the federal Substance Abuse and Mental Health Administration (SAMHSA) on April 24, 2026. It informs medical professionals that going forward, federal grant funding for treatment of opioid use disorder will focus on holistic care models that address the psychosocial needs of individuals with OUD, rather than medication-only models. The letter outlines core clinical tenets and provides new language that will be included in updated terms and conditions for current grantees and future new funding announcements for treatment and training and technical assistance.